By HEATHER HOLLINGSWORTH

AP – COVID-19 deaths in the U.S. have climbed to an average of more than 1,900 a day for the first time since early March, with experts saying the virus is preying largely on a distinct group: 71 million unvaccinated Americans.

The increasingly lethal turn has filled hospitals, complicated the start of the school year, delayed the return to offices and demoralized health care workers.

“It is devastating,” said Dr. Dena Hubbard, a pediatrician in the Kansas City, Missouri, area who has cared for babies delivered prematurely by cesarean section in a last-ditch effort to save their mothers, some of whom died. For health workers, the deaths, combined with misinformation and disbelief about the virus, have been “heart-wrenching, soul-crushing.”

Twenty-two people died in one week alone at CoxHealth hospitals in the Springfield-Branson area, a level almost as high as that of all of Chicago. West Virginia has had more deaths in the first three weeks of September — 340 — than in the previous three months combined. Georgia is averaging 125 dead per day, more than California or other more populous states.

“I’ve got to tell you, a guy has got to wonder if we are ever going to see the end of it or not,” said Collin Follis, who is the coroner in Missouri’s Madison County and works at a funeral home.

The nation was stunned back in December when it was witnessing 3,000 deaths a day. But that was when almost no one was vaccinated.

Now, nearly 64% of the U.S. population has received at least one dose of the COVID-19 vaccine. And yet, average deaths per day have climbed 40% over the past two weeks, from 1,387 to 1,947, according to data from Johns Hopkins University.

Health experts say the vast majority of the hospitalized and dead have been unvaccinated. While some vaccinated people have suffered breakthrough infections, those tend to be mild.

The number of vaccine-eligible Americans who have yet to get a shot has been put at more than 70 million.

“There is a very real risk you’ll end up in the hospital or even in the obituary pages,” Dr. Bruce Vanderhoff, chief medical officer for the Ohio Department of Health, said to the unvaccinated. “Don’t become a statistic when there is a simple, safe and effective alternative to go out today and get vaccinated.”

Many low-vaccination communities also have high rates of conditions like obesity and diabetes, said Dr. William Moss of Johns Hopkins. And that combination — along with the more contagious delta variant — has proved lethal.

“I think this is a real failure of society and our most egregious sin to be at this stage where we have hospitals overwhelmed, ICUs overwhelmed and hitting this mark in terms of deaths per day,” Moss lamented.

New cases of the coronavirus per day in the U.S. have dropped since the start of September and are now running at about 139,000. But deaths typically take longer to fall because victims often linger for weeks before succumbing.

In Kansas, 65-year-old cattleman Mike Limon thought he had beaten COVID-19 and went back to work for a few days. But the virus had “fried” his lungs and he died last week, said his grandson, Cadin Limon, 22, of Wichita.

He said his grandfather didn’t get vaccinated for fear of a bad reaction, and he hasn’t gotten the shot either for the same reason, though serious side effects have proved extremely rare.

He described his grandfather as a “man of faith.”

“Sixty-five is still pretty young,” the young man said. “I know that. It seems sudden and unexpected, but COVID didn’t surprise God. His death wasn’t a surprise to God. The God I serve is bigger than that.”

Cases are falling in West Virginia from pandemic highs, but deaths and hospitalizations are expected to continue increasing for as many as six more weeks, said retired National Guard Maj. Gen. James Hoyer, who leads the state’s coronavirus task force.

Dr. Greg Martin, who is president of the Society of Critical Care Medicine and practices mostly at Grady Hospital in Atlanta, said the staff is buckling under the strain.

“I think everyone in 2020 thought we would get through this. No one really thought that we would still be seeing this the same way in 2021,” he said.

Wyoming Gov. Mark Gordon activated the state’s National Guard on Tuesday to provide assistance to hospitals dealing with a surge of COVID-19 patients.

In Oklahoma, Hillcrest South Hospital in Tulsa is among several medical centers around the country to add temporary morgues. Deaths are at an all-time high there, at three to four times the number it would see in a non-COVID-19 world, said Bennett Geister, hospital CEO.

He said the staff there, too, is worn out.

“They didn’t sign up to be ICU nurses only to have people pass away on them,” he said. “They signed up to be ICU nurses to take people to recovery and heal people from the brink of death.”

By EDITH M. LEDERER

NEW YORK (AP) — In person and on screen, world leaders returned to the United Nations’ foremost gathering for the first time in the pandemic era on Tuesday with a formidable, diplomacy-packed agenda and a sharply worded warning from the international organization’s leader: “We face the greatest cascade of crises in our lifetime.”

Secretary-General Antonio Guterres rang the alarm in his annual state-of-the-world speech at the opening of the U.N. General Assembly’s high-level meeting for leaders of its 193 member nations. More than 100 heads of state and government kept away by COVID-19 are returning to the U.N. in person for the first time in two years. But with the pandemic still raging, about 60 will deliver pre-recorded statements over coming days.

“We are on the edge of an abyss — and moving in the wrong direction,” Guterres said. “I’m here to sound the alarm. The world must wake up.”

Guterres said people may lose faith not only in their governments and institutions but in basic values when they see their human rights curtailed, corruption, the reality of their harsh lives, no future for their children — and “when they see billionaires joyriding to space while millions go hungry on Earth.”

Nevertheless, the U.N. chief said he does have hope.

Guterres urged world leaders to bridge six “great divides”: promote peace and end conflicts, restore trust between the richer north and developing south on tackling global warming, reduce the gap between rich and poor, promote gender equality, ensure that the half of humanity that has no access to the Internet is connected by 2030, and tackle the generational divide by giving young people “a seat at the table.”

Other pressing issues on the agenda of world leaders include rising U.S.-China tensions, Afghanistan’s unsettled future under its new Taliban rulers and ongoing conflicts in Yemen, Syria and Ethiopia’s embattled Tigray region.

The three most closely watched speakers on Tuesday morning are U.S. President Joe Biden, appearing at the U.N. for the first time since his defeat of Donald Trump in the U.S. election last November; Chinese President Xi Jinping, who in a surprise move will deliver a video address; and Iran’s recently elected hardline President Ebrahim Raisi.

The General Assembly’s president, Abdulla Shahid of the Maldives, opened debate by challenging delegates to rise to the occasion. “There are moments in time that are turning points,” he said. “This is one such moment.”

In his speech, Biden, too, called this moment “an inflection point in history” and said that for the United States to prosper, it “must also engage deeply with the rest of the world.”

Ahead of the opening, Guterres warned the world could be plunged into a new and probably more dangerous Cold War unless the United States and China repair their “totally dysfunctional” relationship.

The U.N. chief said in an interview this weekend with The Associated Press that Washington and Beijing should be cooperating on the climate crisis and negotiating on trade and technology, but “unfortunately, today we only have confrontation” including over human rights and geostrategic problems mainly in the South China Sea.

Biden, in his speech, insisted he was “not seeing a new Cold War or a world divided” and said Washington is ready to work with any nation, “even if we have intense disagreement in other areas.”

On the latest speakers list released earlier this month, China’s speech was supposed to be delivered on Friday by a deputy prime minister. But the U.N. confirmed Monday that Xi will give the country’s video address instead. His speech and any comments about the U.S. rivalry are certain to be closely watched and analyzed: China’s presence in the world, and its relationship with the United States, affect most every corner of the planet.

Other leaders scheduled to speak in person during the meeting, which ends Sept. 27, include King Abdullah II of Jordan, the president of Venezuela, and the prime ministers of Japan, India and the United Kingdom along with Israel’s new Prime Minister Naftali Bennett and Palestinian President Mahmoud Abbas.

Leaders delivering prerecorded statements this year include the presidents of Egypt, Indonesia, South Africa and Zimbabwe. French President Emmanuel Macron was supposed to deliver a pre-recorded statement on Tuesday, but the government said Foreign Minister Jean-Yves Le Drian will now deliver the country’s address virtually on the final day.

France and China have reacted angrily to the surprise announcement by Biden, alongside the leaders of Australia and Britain, of a deal to provide Australia with at least eight nuclear-powered submarines. Australia had signed a contract worth at least $66 billion for a dozen French conventional diesel-electric submarines and their construction was already under way.

Le Drian told a news conference Monday that there is a “crisis of trust” between the United States and its oldest ally, France, as well as Europe, which has been excluded from the new US-UK-Australia alliance focused on the Indo-Pacific and aimed at confrontation with China. He said Europeans “should not be left behind,” and need to define their own strategic interests.

By tradition, the first country to speak was Brazil, whose president, Jair Bolsonaro, isn’t vaccinated. He reiterated last Thursday that he doesn’t plan to get the shot any time soon, justifying his refusal by saying he had COVID-19 and therefore has a high level of antibodies.

A key issue ahead of the meetings has been COVID-19 entry requirements for leaders to the United States — and to the U.N. headquarters itself. The U.S. requires a vaccination or a recent COVID-19 test, and the U.N. will operate on an honor system whereby anyone entering the complex attests that they do not have symptoms and have not tested positive in the last 10 days.

Guterres, in his opening speech, pointed to “supersized glaring inequalities” sparked by the COVID-19 pandemic, climate alarm bells “ringing at fever pitch,” upheavals from Afghanistan to Ethiopia and Yemen thwarting global peace, a surge of mistrust and misinformation “polarizing people and paralyzing societies” and human rights “under fire.”

The solidarity of nations to tackle these and other crises “is missing in action just when we need it most,” he said. “Instead of humility in the face of these epic challenges, we see hubris.”

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Edith M. Lederer, chief U.N. correspondent for The Associated Press, has been reporting internationally for nearly 50 years. Follow her on Twitter at http://twitter.com/EdithLedererAP